Published Date : 2017-05-17
Down syndrome (trisomy 21) is a condition in which the fetus has extra copy of chromosome 21. It is the most common chromosomal abnormality, which occurs with a frequency of 1 in 700-800 births. It is most common cause of mental retardation. Although this syndrome is more common in women over 35 years of age, most babies with Down syndrome are born to mothers under 35 years. The mother's blood is checked for a combination of different markers. Double screening test is done From 11 to 13 weeks of pregnancy. In this test two hormones are measured : hCG (human chorionic gonadotrophin) & PAPP-A (pregnancy associated plasma protein) Triple screen test is done between the 15th and 20th week of pregnancy although results obtained in the 16th -18th week are said to be the most accurate. In this test three hormones are measured : Alpha-fetoprotein (AFP), Human chorionic gonadotropin (hCG) & Unconjugated estriol (uE3)
Tests are run on Immulite 1000 and risk is calculated using software named PRISCA 5
All you need to do is come to lab with USG report. No need to fast. Samples are collected on all working days. Report is available in 3 working days or earlier. All you need to do is come to lab with USG report.